Search results for "Paroxysmal AF"
showing 6 items of 6 documents
Assisting Electrophysiological Substrate Quantification in Atrial Fibrillation Ablation
2019
[EN] Catheter ablation (CA) is the most popular treatment of atrial fibrillation (AF) with good results in paroxysmal AF, while its efficiency is significantly reduced in persistent AF. With the equipment used for CA strongly depending on electro-gram (EGM) fractionation quantification, the use of a reliable fractionation estimator is crucial to reduce the high recurrence rates in persistent AF. This work introduces a non-linear EGM fractionation quantification technique, which is based on coarse-grained correlation dimension (CGCD) computed over epochs of 1 second. Recordings were firstly normalized, denoised and lowpass filtered. The final CGCD value was calculated by the median CGCD valu…
Atrial fibrillation in highly trained endurance athletes — Description of a syndrome
2016
Atrial fibrillation (AF) is the most common heart arrhythmia, the risk of which typically increases with age. This condition is commonly associated with major cardiovascular diseases and structural heart damage, while it is rarely observed in healthy young people. However, increasing evidence indicates that paroxysmal AF can also onset in young or middle-aged and otherwise healthy endurance athletes (e.g., cyclists, runners and cross-country skiers). Here we review the topic of AF associated with strenuous endurance exercise (SEE), for example cycling, running and cross-country skiing, especially at a competitive level, and we propose the definition of a new syndrome based on the accumulati…
Simplifying atrial fibrillation ablation: how far can we go?
2013
The procedural end point of electrical isolation of the pulmonary veins (PVs) for the treatment of atrial fibrillation (AF) has been debated extensively. After identifying the PVs as the dominant arrhythmogenic site of paroxysmal AF, 2 fundamentally different approaches to the interventional treatment of AF were introduced. Haissaguerre et al developed a technique to electrically isolate the PVs by targeting electrophysiological (EP) breakthroughs from the left atrium to the PVs guided by a circular mapping catheter. In contrast, Pappone et al implemented an anatomical approach that used circumferential ablation lines around the PVs guided by a 3-dimensional mapping system. This latter appr…
Exercising recommendations for paroxysmal AF in young and middle-aged athletes (PAFIYAMA) syndrome.
2017
We have recently described a new syndrome: strenuous endurance exercise-related atrial fibrillation (AF) under the acronym of ‘paroxysmal AF in young and middle-aged athletes’ (‘PAFIYAMA’). Provided that other risk factors for AF and underlying conditions have been excluded (1), the diagnostic criteria for this syndrome entail a number of conditions, classified as major and minor. An enhanced risk of AF has been clearly documented in endurance athletes (top-class, elite and recreational) (2-5), and such risk typically ranges between 1.2- to 15-fold compared to the general, sedentary population (the better cardiovascular fitness, the higher incidence of AF) (6-11). Anecdotally, the last auth…
Reliable Paroxysmal Atrial Fibrillation Substrate Assessment During Sinus Rhythm Through Optimal Estimation of Local Activation Waves Dynamics
2020
[EN] The analysis of coronary sinus (CS) electrograms (EGMs) during catheter ablation (CA) of atrial fibrillation (AF) is highly important for AF substrate evaluation. However, channels of the CS catheter may be affected by vigorous cardiac movement and bad contact. This work investigates the most reliable channels in preserving the AF dynamics during sinus rhythm (SR). Local activation waves (LAWs) were detected in 44 bipolar CS recordings of 60-300 seconds duration in 28 paroxysmal AF patients undergoing CA. Recordings consisted of five channels: distal, mid-distal, medial, mid-proximal and proximal. LAW duration, amplitude, area and correlation between dominant morphologies of each chann…
Analysis of inter-atrium differences in paroxysmal and persistent atrial fibrillation using principal component analysis
2007
The pathophysiological mechanisms of atrial fibrillation (AF) are not entirely clear yet, and there is no full explanation for the development and evolution of the arrhythmia. The goal of this study is to find inter-atrium differences in electrophysiological behavior between persistent and paroxysmal AF. The database analyzed contains intra-cardiac records from 14 patients with paroxysmal AF and 10 with persistent AF. Dominant frequency and sample entropy measurements showed that in the paroxysmal group there was a left-to-right gradient. These differences were enhanced after the extraction of the main components with principal component analysis. These findings may be interpreted as a poss…